(LONDON) -- At least six people were shot dead at Jerusalem's Ramot Junction on Monday, Israeli police and emergency services said.
Two suspects were also shot and killed at the scene, police said.
The attackers opened fire at people waiting at a bus depot, police said, before boarding a bus to continue the attack.
At least 20 people were also injured in the shooting, Israeli emergency services said.
An off-duty soldier and civilians at the bus stop fired at the two attackers, killing them, according to an Israeli police spokesperson.
One suspect has been arrested amid the investigation into the shooting, police said Monday.
"Earlier today, detectives from the Jerusalem District Central Investigations Unit, acting under the guidance of the ISA, arrested a suspect from eastern Jerusalem. His involvement in the attack is currently under investigation,” the Israeli Police Spokesperson's unit said in a statement.
Visiting the scene, Israeli Prime Minister Benjamin Netanyahu said, "We are at war, a fierce war against terrorism on several fronts," according to a readout published by his office.
"We are fighting terrorism -- the terrorist regime of the Houthi, Iran that backs everyone, in Gaza, Lebanon, Hezbollah, in all sectors," the prime minister said. "We are not letting up and we will not let up. We are nailing our actions, and we will achieve all our goals."
"We are now pursuing and surrounding the villages from which the murderers came," Netanyahu said. "We will catch everyone who helped them, everyone who sent them."
ABC News' Joe Simonetti, Jordana Miller and Somayeh Malekian contributed to this report.